Women older than 50 who eat
high-protein diets could have a greater risk of heart failure, especially if a
lot of their protein comes from meat, according to a new study presented at the
annual scientific conference of the American Heart Association.
Researchers found that
postmenopausal women who follow a high-protein diet had a significantly higher
rate of heart failure than those who ate less protein daily or ate more
vegetable protein.
The study examined the
dietary protein intake of 103,878 women, ages 50 to 79, from 1993 to 1998. They
self-reported their daily diets, which researchers noted can be unreliable;
researchers also used biomarker data to determine actual amounts of dietary
protein. Although all participants were free of heart failure during that
period, about 1,700 of them developed heart failure by 2005.
Researchers adjusted for age,
education, race or ethnicity and heart failure risk factors such as high blood
pressure, diabetes, coronary artery disease, anemia or atrial fibrillation.
"We found that by increasing
the total dietary protein intake, there was a statically significant increase
in the incidence of heart failure," said Dr. Mohamad Barbour, an internist
at the Alpert Medical School of Brown University, Memorial Hospital of Rhode
Island and lead author of the study.
In
fact, the risk was almost double.
Meanwhile, women whose
proteins were sourced mainly from vegetables appeared to be at a lower risk of
heart failure. This could be
attributed to the molecular mechanisms of animal protein, Barbour said,
explaining that animal proteins can turn to toxic molecules, which can in turn
affect the function of the heart's left ventricle and lead to heart failure.
They can also increase the body mass index, a known risk factor for heart
failure.
"Our study should be
interpreted with caution," warned Barbour. "It appears that a
high-protein diet may increase the risk of heart failure among postmenopausal
women; however, more research will be needed."
Dr. Mingyang Song, a researcher at
Massachusetts General Hospital and the Harvard T.H. Chan School of Public
Health, described the findings as interesting. Song was the lead author of
research published this year that found replacing animal protein with plant
protein in a person’s diet was associated with a decreased risk of death. He
was not involved in the new research.
"People who eat high vegetable
proteins may also have a healthier lifestyle," Song said. This may imply
that other factors are responsible for lowering the risk of heart failure for
that group, he added.
"I think it'll be good to
replicate the results in other studies," he said, suggesting that a more controlled
group with a more controlled food intake could be required for that purpose.
Source:
http://edition.cnn.com
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