Preventing enzymes in hair follicles promotes hair growth

Blocking of enzymes inside hair follicles that are suspended in a resting state restores hair growth, a new study from researchers at Columbia University Medical Center has found.

In experiments with mouse and human hair follicles, Angela M. Christiano, PhD, and colleagues found that drugs that inhibit the Janus kinase (JAK) family of enzymes promote rapid and robust hair growth when directly applied to the skin.

The study raises the possibility that drugs known as JAK inhibitors could be used to restore hair growth in multiple forms of hair loss such as that induced by male pattern baldness, and additional types that occur when hair follicles are trapped in a resting state. Two JAK inhibitors have been approved by the U.S. Food and Drug Administration. One is approved for treatment of blood diseases (ruxolitinib) and the other for rheumatoid arthritis (tofacitinib). Both are being tested in clinical trials for the treatment of plaque psoriasis and alopecia areata, an autoimmune disease that causes hair loss.

"What we've found is promising, though we haven't yet shown it is effective for male pattern baldness," said Dr. Christiano. "More work needs to be done to test formulations of JAK inhibitors specially made for the scalp to determine whether they can induce hair growth in humans."

Christiano and her colleagues serendipitously discovered the effect of JAK inhibitors on hair follicles when they were studying a type of hair loss known as alopecia areata, caused by an autoimmune attack on the hair follicles. Christiano and colleagues reported last year that JAK inhibitors shut off the signal that provokes the autoimmune attack, and that oral forms of the drug restore hair growth in some people with the disorder.

In the course those experiments, Dr. Christiano noticed that mice grew more hair when the drug was applied topically to the skin than when given internally. This suggested JAK inhibitors might have a direct effect on the hair follicles in addition to inhibiting the immune attack.

When the researchers looked more closely at normal mouse hair follicles, they found that JAK inhibitors rapidly awakened resting follicles out of dormancy. Hair follicles do not produce hair constantly but rather by cycling between resting and growing phases.

JAK inhibitors trigger the follicles' normal reawakening process, the researchers found. Mice treated for five days with one of two JAK inhibitors sprouted new hair within 10 days, greatly accelerating the hair follicle growth phase. No hair grew on untreated control mice in the same time period.

Enzymes can be prevented in the hairs by applying one of these two natural  products which is very popular in Asia.

Asian ladies like using natural mixtures packaged in the form of cream/oil to retain their hairs and its longevity.

Two of such products are:

1.     AMLA+ REETHA + SIKAKAI +EGG YOLK HERBAL HAIR OIL (120 ml) 

                    Features:

Blend of four oils in a bottle egg yolk oil- Egg oil helps recreate and maintains the texture of hair- an excellent natural hair nutrient for dry scalp, nourishes hair, natural softness.

Acts as a humectant drawing moisture in as it conditions.

Egg oil averts falling of hair, prevents premature graying and strengthens hair with regular use.

 It has superior nourishing and conditioning property which help in reducing the onset of premature hair loss.

 Egg oil also promotes the growth of new hair

REETHA OIL (Soap-nut tree) is well known for hair care & hair growth, also good for oily hair.

SIKAKAI means "fruit for hair". It is made from Acacia concinna, a shrub native to the warm, plains of central and south India. Acacia concinna has been used for hair care in India for centuries.

AMLA OIL: Regular use of amla strengthens the hair follicles, stimulates hair growth, keeps dandruff away, straightens your hair, prevents split ends and nourishes your hair. It also prevents premature graying of hair and stops hair loss.

ALL FOUR OILS BECOME SUPER FOOD FOR HAIR GROWTH WHEN USED IN COMBINATION .

For Both Men & Women, All Types of Hair

People who know me can attest the to the fact that don’t recommend product(s) easily to the public without doing thorough underground research about it.

This product is good and I recommend it to anyone who cares about her hairs and looks.

The benefits of this product are that, it makes your hair thick, dark, shiny, lustrous, fuller, beautiful & healthy.

Customers’ review of the product:

4.0 out of 5 s

By Catza Juarez on March 11, 2016

              During the use of the product im getting beautiful hair. Im Sattisfied so far

By annie on June 30, 2016

I just reordered the second bottle of this the only bad thing about it was I got a smaller bottle then the first original bottle. This product is amazing my hair has been thinning recently so I came across this product thought to use it and it's the best product I've used! I use it with herbal essence actually works I recommend this product def!

By Rachel Balkcom on July 12, 2015

Like the egg oil, this smells funny (actually, they smell identical), but it too leaves my hair soft and shiny.

Place your order here:   http://amzn.to/2azIUpm

Your Money (100%) will be refunded if you are not satisfied for any reasons. Buy with Confidence - NO RISK. FREE SHIPPING

You can as well, try the 2^nd product; they are all very good and effective.

                     NO 2 PRODUCT:

2.    Argan Tree Morocco Gaga Oil For Hair

                          Features

100% Organic Certified & Imported from Morocco.

Added with snail essence & other fruits extract.

Prevents Frizz & Revitalizes Natural Hair Shine & Silkiness -

MOISTURIZER AND HEALS DRY HAIR - naturally freshens, hydrates and softens dry hair, it also repairs and beautifies natural hair, from roots to split-ends and improves scalp health.

Rich in VITAMIN E, NATURAL FATTY ACIDS and OMEGA 6 - Argan Oil is a natural prime antioxidant combating premature ageing skin. Quickly absorbs and deeply penetrates to heal, nourish and hydrate.

Ultra-light miracle argan oil leaves No residue and No oil build up, only provides silky finish and brilliant shine.

 Apply a few drops as often as needed to achieve soft, shiny hair.

Testimonies

By Wenhsin Lin on September 12, 2015

I got it in 4 days with free shipping. It smells so good and it really makes your hair smooth. I love it!!! Very nice product!

By Melanie on March 6, 2016

I am amazed how well this product works!
Definitely will buy again!

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100% GUARANTEE - Purchase with complete peace of mind, if you are not completely satisfied with Argan Tree Gaga Certified Organic Oil, a refund of your entire order will be made within 90 days of purchase.  FREE SHIPPING.