Once you reach the age of 30, you have a 10 percent to 20 percent chance of graying hair with each passing decade. It's a fact of life that, eventually, virtually everyone will go gray.
Your hair color comes from pigment called melanin. Each hair may contain dark melanin (eumelanin) and light melanin (pheomelanin), which blend together to form the many shades of hair color among humans.
When you're young, special pigment stem cells called melanocytes inject pigment into keratin-containing cells.
This keratin, a protein, makes up your hair and is responsible for giving it its color. As you age, melanin is reduced, which is why your hair turns gray and, ultimately, white i.e this means there's no melanin left.
Scientists Discover Gene Linked to Graying HairWhat exactly causes melanin to be reduced and hair to turn gray has remained a mystery, until now. An international team of researchers has discovered the first gene linked to gray hair.
The study involved a genome-wide association scan in more than 6,000 Latin Americans to look for genes related to features of scalp hair and facial hair, including graying, balding, beard thickness, monobrow, eyebrow thickness and more).
A gene that has previously been linked to blonde hair in Europeans turned out to be connected to gray hair as well and accounted for about 30 percent of hair graying among the study participants.
The other 70 percent is likely due to factors such as age, environment, stress and more. The researchers plan to look for ways to manipulate this genetic pathway to prevent hair from turning gray (including drugs, which I would not recommend taking for the purpose of changing your hair color).
What Else Causes Gray Hair?Other factors for why hair turns gray include:
• Hydrogen peroxide: Hydrogen peroxide is a well-known tool for bleaching your hair, but many people aren't aware that your hair cells make hydrogen peroxide, too.
As you age, the amount produced increases, which researchers believe ultimately bleaches out your hair pigment, turning your hair grey and then white.
• Smoking: There is a significant association between tobacco use and graying of hair. Cigarette smoking is also linked to premature hair graying, with the onset of gray hair occurring before the age of 30.
• Oxidative stress: Oxidative stress can be defined as the state in which your free radicals (from pollution, poor diet, stress, etc.) outnumber your antioxidant defenses (from healthy diet). Graying hair may be an indicator of oxidative stress-induced damage.
Research has also shown that people with premature graying had a higher level of pro-oxidants and lower levels of antioxidants than those with normal hair.
• Vitamin B12 deficiency: This is also linked to premature gray hair, and there is at least one report of pigmentation returning to hair after the vitamin deficiency was resolved.
Is Premature Gray Hair an Indicator of Health Problems?It's thought that going prematurely gray is largely genetic; if you have family members who turned gray early on, there's a chance you might too.
Obesity is also associated with premature graying, and there is some speculation that it could be an indicator of certain health issues. For instance, premature graying of hair may be an important risk marker for the bone condition osteopenia.
According to research published in The Journal of Clinical Endocrinology and Metabolism, people with premature graying but no other identifiable risk factor were 4.4 times as likely to have osteopenia as those without premature graying. The researchers suggested:
Does Stress Cause Gray Hair?It's commonly believed that stress causes gray hairs (and many parents of teenagers or former presidents, whose hair often turns gray during office would likely attest to that).
Science on this topic has frequently come up short, save a 2011 study published in the journal Nature and led by Nobel Prize winner Dr. Robert Lefkowitz.16
That study found chronic stress and frequent activation of the "fight or flight" stress response leads to DNA damage that may promote not only aging, cancer, neuropsychiatric conditions and miscarriages but also affect genes that control hair pigment.
Scientists Reveal Two Potential 'Cures' for Gray HairResearchers believe they are getting closer to finding a cure for gray hair. Scientists at New York University's Langone Medical Center, for instance, isolated the Wnt protein, which coordinates pigmentation between melanocytes and another type of stem cell that guides the development of hair follicles.
When the researchers inhibited the Wnt pathway in black mice, they turned gray. They believe that one day adding the Wnt protein to hair care products or supplements may "cure" gray hair.
Meanwhile, in a follow-up to the original study that linked gray hair to a build up of hydrogen peroxide, researchers revealed that a UVB-activated compound called PC-KUS could reverse the hydrogen peroxide build up and effectively "cure" gray hair.
The treatment also works to restore skin color in people with vitiligo. Dr. Gerald Weissmann, editor-in-chief of The FASEB Journal, which published the study, told Medical News Today:
The search for a cure for gray hair assumes that gray hair is a problem that needs solving. But there's nothing intrinsically bad about having gray hair. In fact, from a health perspective you're far better off going gray than using toxic hair dyes.
And if you're thinking of embracing your silver locks, now's a perfect time. So-called "granny hair" is the latest trend, with people paying salons big bucks to go gray. If you're lucky enough to have earned your gray naturally, you can get this look for free. New York hair stylist Jan-Marie Arteca told Reuters: